The natural form of nicotine (C10H14N2) is a parasympathomimetic substance (stimulant or cholinergic drug). It is produced in many plants throughout the Solanaceae (Deadly Nightshade) family. The most well-known to produce this alkaloid are in the Nicotiana genus, containing the “tobacco plant,” species Nicotiana Tabacum. Nicotine can also be found in small quantities in tomatoes, potatoes, eggplant, bell peppers and even the coca plant. The…
What are Cannabis Concentrates? Cannabis Concentrates are simply cannabinoids (usually THCA, or CBDA which turn to THC and CBD with heat) extracted and concentrated from dried or fresh marijuana. How are they made? Separation can be done with sifters (Hash), presses (rosin), or solvents (tinctures, wax, oils, crumble, shatter). Solvents include alcohol to make products like Rick Simpson oil, CO2 (Co2 Oil), Butane (BHO or…
Opioids and the Human Body: Receptors evolved in the human body to recognize Endogenous Opioids. These are chemicals produced naturally to help regulate pain after injuries or in highly stressful situations. Our bodies release naturally occurring endogenous opioids in the form of neurotransmitters, like endorphins. Opioid Receptors like the µ (MU) Opioid Peptide Receptor, are found spread throughout the body. When someone is injured the brain releases…
Nicotine Salt vs. Freebase Nicotine When using a vape or e-cig, users are exposed to either liquid “Nicotine Salt” or “freebase” nicotine. Although both are forms of nicotine, they interact with the body very differently. First came Freebase Nicotine in the 60’s when cigarette companies laced tobacco with salt-like diammonium phosphate to release ammonium (ammonia) when the cigarette combusts changing natural nicotine to base form….
Internal and external stimuli (life) cause changes in the limbic system (emotions) while down regulation from active use of substances impacts survival functions (withdrawal & desperation) and dampens signals to the prefrontal cortex (addictive behaviors) so the cycle of trigger, motivation, behavior, short term reward is reinforced and problem solving and resilience are diminished (chronic relapse). If you are struggling with any addiction, don’t hesitate to…